Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | SCN4A | P35499 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4523312 | 0.81 | GAA (0.41) | L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL11131977 | 0.80 | FFAR4 (0.43) | FFAR4FFAR1SMN1; SMN2 | |
| SCHEMBL334185 | 0.80 | TTR (0.41) | TTRFFAR4FFAR1SCN4ACRHBP | |
| SCHEMBL4575838 | 0.79 | TTR (0.54) | TTRCRHBPCRHR2SMN1; SMN2KDM4E | |
| SCHEMBL10852995 | 0.77 | FFAR4 (0.62) | TTRFFAR4FFAR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2718192 | 0.77 | SCN4A (0.40) | TTRFFAR4FFAR1SCN4ASMN1; SMN2 | |
| SCHEMBL9665251 | 0.77 | SCN4A (0.51) | SCN4ASMN1; SMN2MRGPRX4KDM4E | |
| SCHEMBL293026 | 0.76 | SMN1; SMN2 (0.49) | L3MBTL1SMN1; SMN2MRGPRX4KDM4E | |
| SCHEMBL5645536 | 0.76 | PPARD (0.51) | FFAR4FFAR1 | |
| SCHEMBL10088644 | 0.74 | CSNK2A1 (0.49) | TTRFFAR4FFAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100349856-C | Propionic acid derivatives and their use as hPPAR activators | SMITHKLINE BEECHAM CORP (US) | 2007-11-21 | — | — | CN | disclosed |
| CN-1675168-A | Propionic acid derivatives and their use as hPPARs activators | SMITHKLINE BEECHAM CORP (US) | 2005-09-28 | — | — | CN | disclosed |