Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL27628779

O=C(O)C(F)(F)F.O=C(O)C1=Cc2ccccc2OC1C(F)(F)F

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 19/20 0.60
PTGS1 P23219 11/20 0.60
P2RY6 Q15077 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27916566 0.95 PTGS2 (0.65) PTGS2PTGS1P2RY6
SCHEMBL6093316 0.95 PTGS2 (0.65) PTGS2PTGS1P2RY6
SCHEMBL4751105 0.95 PTGS2 (0.65) PTGS2PTGS1P2RY6
Fluoride SCHEMBL28028189 0.94 PTGS2 (0.63) PTGS2PTGS1P2RY6
SCHEMBL27648680 0.94 PTGS2 (0.63) PTGS2PTGS1P2RY6
Benzene SCHEMBL6629703 0.89 PTGS2 (0.62) PTGS2PTGS1
SCHEMBL5667657 0.81 P2RY6 (0.55) PTGS2PTGS1P2RY6
SCHEMBL6094984 0.79 PTGS2 (0.67) PTGS2PTGS1
SCHEMBL6094453 0.79 PTGS2 (0.59) PTGS2PTGS1
SCHEMBL6094976 0.79 PTGS2 (0.67) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1768050-A Benzopyran compounds for the treatment of inflammation PHARMACIA CORP (US) 2006-05-03 CN disclosed