Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283338 | 0.89 | TBXAS1 (0.54) | TBXA2RTBXAS1TDP1KMT2A | |
| SCHEMBL11283342 | 0.89 | TBXAS1 (0.54) | TBXA2RTBXAS1TDP1KMT2A | |
| Hydrochloric Acid SCHEMBL11266012 | 0.87 | TBXAS1 (0.55) | TBXA2RTBXAS1TDP1 | |
| Bicarbonate SCHEMBL28519256 | 0.86 | KDM4E (0.49) | TBXA2RTBXAS1KMT2A | |
| Propionic Acid SCHEMBL28145486 | 0.86 | KDM4E (0.51) | TBXAS1ALDH1A1KMT2A | |
| Bicarbonate SCHEMBL28144511 | 0.85 | KDM4E (0.54) | TBXAS1ALDH1A1KMT2A | |
| SCHEMBL15153572 | 0.85 | TBXA2R (0.51) | TBXA2RTBXAS1GPR84PPARGPPARD | |
| SCHEMBL15153349 | 0.85 | TBXA2R (0.51) | TBXA2RTBXAS1GPR84PPARGPPARD | |
| SCHEMBL15153406 | 0.85 | TBXA2R (0.51) | TBXA2RTBXAS1GPR84PPARGPPARD | |
| SCHEMBL15153456 | 0.85 | TBXA2R (0.51) | TBXA2RTBXAS1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1651089-A | Nontoxic ionic liquid, preparation method and application thereof | UNIV HEBEI NORMAL (CN) | 2005-08-10 | — | — | CN | disclosed |