Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798335 | 0.85 | CA12 (0.62) | CA12CA1CA2CA9HDAC8 | |
| SCHEMBL2491952 | 0.84 | HDAC8 (0.53) | CA12CA1CA2CA9HDAC8 | |
| SCHEMBL27766713 | 0.83 | HTR7 (0.46) | CA12CA1CA2CA9TAAR1 | |
| SCHEMBL27942786 | 0.83 | TAAR1 (0.48) | CA12CA1CA2CA9TAAR1 | |
| SCHEMBL30122908 | 0.83 | CA12 (0.66) | CA12CA1CA2CA9HDAC8 | |
| SCHEMBL28089504 | 0.83 | TAAR1 (0.68) | TAAR1HRH3LOXL2ADRB2 | |
| SCHEMBL10600163 | 0.82 | CHRNB4 (0.50) | CA12CA1CA2CA9HDAC8 | |
| SCHEMBL15345544 | 0.82 | CSNK2A1 (0.53) | CA12CA1CA2CA9TAAR1 | |
| SCHEMBL15345596 | 0.82 | CSNK2A1 (0.53) | CA12CA1CA2CA9TAAR1 | |
| SCHEMBL20434263 | 0.81 | HDAC8 (0.50) | CA12CA1CA2CA9HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193566-B | A kind of novel method of synthesizing 2-bromonaphthalene compounds | ZHEJIANG UNIVERSITY (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-101279890-A | Polysubstituted acene derivative and preparation thereof | CHINESE ACAD INST CHEMISTRY (CN) | 2008-10-08 | — | — | CN | disclosed |
| CN-1766678-A | Phase aberration film production method and phase aberration film produced by the method,polarization sheet using same and liquid crystal display | KONICA MINOLTA OPTO INC (JP) | 2006-05-03 | — | — | CN | disclosed |