SCHEMBL27629323

SCHEMBL27629323

Oc1ccc(Cn2cnnn2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58
KDM4E B2RXH2 1/20 0.53
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ALDH1A1 P00352 2/20 0.51
MAPT P10636 1/20 0.50
HMOX1 P09601 1/20 0.41
HTR1A P08908 1/20 0.41
HTR2C P28335 1/20 0.41
ALPG P10696 1/20 0.41
ESR1 P03372 3/20 0.39
ESR2 Q92731 2/20 0.39
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
ATM Q13315 1/20 0.39
RCE1 Q9Y256 1/20 0.39
CYP19A1 P11511 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10066409 0.84 MEN1 (0.54) MEN1KMT2ACYP1A2CYP2C9KDM4E
SCHEMBL23913862 0.84 MAPK1 (0.53) MEN1KMT2ACYP1A2CYP2C9KDM4E
SCHEMBL708243 0.82 KDM4E (0.51) MEN1KMT2ACYP1A2CYP2C9KDM4E
SCHEMBL10053477 0.82 MEN1 (0.53) MEN1KMT2ACYP1A2CYP2C9KDM4E
SCHEMBL4833617 0.82 MEN1 (0.53) MEN1KMT2ACYP1A2CYP2C9KDM4E
SCHEMBL29788840 0.82 ALDH1A1 (0.65) MEN1KMT2ACYP1A2CYP2C9KDM4E
SCHEMBL2532477 0.82 CYP19A1 (0.55) MEN1KMT2ACYP1A2CYP2C9KDM4E
SCHEMBL21708921 0.80 ALDH1A1 (0.59) MEN1KMT2ACYP1A2CYP2C9KDM4E
SCHEMBL9584318 0.80 KDM4E (0.49) MEN1KMT2ACYP1A2CYP2C9KDM4E
SCHEMBL9978689 0.80 CYP19A1 (0.53) MEN1KMT2ACYP1A2CYP2C9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1736976-A Use of aluminum nitrate in aromatic ring nitration NANJING UNIVERSITY OF TECHNOLOGY (CN) 2006-02-22 CN disclosed