Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.58 |
| ▸ | PPARA | Q07869 | 13/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12038079 | 0.95 | HRH3 (0.59) | PPARGPPARAPPARDHRH3KDM4E | |
| SCHEMBL10058004 | 0.89 | HRH3 (0.62) | PPARGPPARAPPARDHRH3KDM4E | |
| SCHEMBL5544269 | 0.86 | PPARG (0.57) | PPARGPPARAPPARDHRH3KDM4E | |
| SCHEMBL5854753 | 0.86 | PPARG (0.57) | PPARGPPARAPPARDHRH3KDM4E | |
| SCHEMBL5858351 | 0.86 | PPARG (0.60) | PPARGPPARAPPARDHRH3KDM4E | |
| SCHEMBL5857599 | 0.85 | PPARG (0.62) | PPARGPPARAPPARDHRH3KDM4E | |
| SCHEMBL5538021 | 0.85 | PPARG (0.59) | PPARGPPARAPPARDHRH3KDM4E | |
| SCHEMBL27629717 | 0.85 | PPARA (0.56) | PPARGPPARAPPARDHRH3 | |
| SCHEMBL5856033 | 0.85 | PPARG (0.59) | PPARGPPARAPPARDHRH3KDM4E | |
| SCHEMBL5022312 | 0.84 | KDM4E (0.61) | PPARGPPARAPPARDHRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |