⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110384 | 0.74 | — | — | |
| SCHEMBL357742 | 0.74 | — | — | |
| SCHEMBL367002 | 0.74 | — | — | |
| SCHEMBL30292849 | 0.69 | — | — | |
| SCHEMBL9114090 | 0.66 | — | — | |
| SCHEMBL17184812 | 0.64 | HCAR2 (0.44) | — | |
| SCHEMBL446103 | 0.63 | — | — | |
| SCHEMBL16030179 | 0.63 | FBP1 (0.38) | — | |
| SCHEMBL709112 | 0.62 | MEN1 (0.54) | — | |
| Hydrochloric Acid SCHEMBL29165508 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |