Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28753498 | 0.84 | HTR2B (0.40) | — | |
| SCHEMBL7766488 | 0.77 | HTT (0.35) | — | |
| SCHEMBL28756718 | 0.74 | ALDH1A1 (0.37) | MTNR1ANOTUM | |
| SCHEMBL14192984 | 0.61 | KMT2A (0.38) | — | |
| SCHEMBL5538135 | 0.61 | NOTUM (0.46) | DRD2NOTUM | |
| SCHEMBL5546718 | 0.61 | TP53 (0.49) | — | |
| SCHEMBL5591074 | 0.60 | ALDH1A1 (0.47) | — | |
| SCHEMBL3289588 | 0.60 | ALDH1A1 (0.47) | — | |
| SCHEMBL5541619 | 0.59 | HSD17B3 (0.38) | NOTUM | |
| SCHEMBL5540462 | 0.59 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |