Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630102 | 0.86 | P2RX7 (0.32) | — | |
| SCHEMBL27630178 | 0.83 | SMN1; SMN2 (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27650359 | 0.79 | MEN1 (0.33) | — | |
| SCHEMBL1136292 | 0.79 | SLC22A12 (0.43) | — | |
| SCHEMBL27630166 | 0.75 | KMT2A (0.47) | — | |
| SCHEMBL28822452 | 0.72 | MAOB (0.42) | — | |
| SCHEMBL919794 | 0.71 | MAOB (0.49) | — | |
| SCHEMBL920290 | 0.71 | MAOB (0.51) | — | |
| SCHEMBL28033605 | 0.71 | CACNA1C (0.42) | CA12CA9 | |
| SCHEMBL13577209 | 0.71 | CACNA1C (0.42) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | claimed |
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | disclosed |