8-Hydroxy Quinaldine

8-Hydroxy Quinaldine

SCHEMBL27630304

Cc1ccc2cccc(O)c2n1.Oc1ccc(-c2ccccc2)cc1.[GaH3]

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ METAP2 P50579 1/20 0.70
▸ CD74 P04233 1/20 0.46
▸ MIF P14174 1/20 0.46
▸ MMP3 P08254 1/20 0.46
▸ BCL2L1 Q07817 1/20 0.46
▸ KDM4E B2RXH2 3/20 0.45
▸ KMT2A Q03164 3/20 0.44
▸ PLAU P00749 1/20 0.44
▸ NCF1 P14598 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ HIF1A Q16665 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ ESR1 P03372 5/20 0.42
▸ ESR2 Q92731 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL27650187 0.98 METAP2 (0.72) METAP2CD74MIFMMP3BCL2L1
8-Hydroxy Quinaldine SCHEMBL195825 0.98 METAP2 (0.72) METAP2CD74MIFMMP3BCL2L1
8-Hydroxy Quinaldine SCHEMBL461474 0.97 METAP2 (0.70) METAP2CD74MIFMMP3BCL2L1
8-Hydroxy Quinaldine SCHEMBL21141877 0.97 METAP2 (0.70) METAP2CD74MIFMMP3BCL2L1
8-Hydroxy Quinaldine SCHEMBL30388211 0.97 METAP2 (0.70) METAP2CD74MIFMMP3BCL2L1
8-Hydroxy Quinaldine SCHEMBL132450 0.97 METAP2 (0.70) METAP2CD74MIFMMP3BCL2L1
8-Hydroxy Quinaldine SCHEMBL5142152 0.97 METAP2 (0.70) METAP2CD74MIFMMP3BCL2L1
8-Hydroxy Quinaldine SCHEMBL28331020 0.95 METAP2 (0.68) METAP2CD74MIFMMP3BCL2L1
8-Hydroxy Quinaldine SCHEMBL28119347 0.95 METAP2 (0.68) METAP2CD74MIFMMP3BCL2L1
8-Hydroxy Quinaldine SCHEMBL28331086 0.92 METAP2 (0.82) METAP2KDM4EKMT2APLAUNCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105304014-B Display device 株式会社日本显示器 2018-04-17 — — CN disclosed
CN-206388485-U Display device 株式会社日本显示器 2017-08-08 — — CN disclosed
CN-106169274-A Display device 株式会社日本显示器 2016-11-30 — — CN disclosed
CN-1794340-B Display device, and method of operation thereof and game machine SEMICONDUCTOR ENERGY LAB 2011-06-29 — — CN disclosed
CN-1794340-A Display device, and method of operation thereof SEMICONDUCTOR ENERGY LAB (JP) 2006-06-28 — — CN disclosed
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