SCHEMBL2763053

SCHEMBL2763053

CC12CC3(C)CC(c4ccc(C#Cc5ccccc5)cc4C#Cc4ccccc4)(C1)CC(C14CC5(C)CC(C)(CC(c6ccc(C#Cc7ccccc7)cc6C#Cc6ccccc6)(C5)C1)C4)(C2)C3

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.37
RARG P13631 8/20 0.37
RARA P10276 7/20 0.37
CYP3A4 P08684 2/20 0.37
CYP26A1 O43174 1/20 0.37
CRABP2 P29373 1/20 0.37
SRD5A1 P18405 1/20 0.34
SRD5A2 P31213 1/20 0.34
GRM5 P41594 6/20 0.33
APP P05067 1/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2846334 0.88 RARB (0.36) RARBRARGRARACYP3A4CYP26A1
SCHEMBL2763805 0.86 RARB (0.35) RARBRARGRARACYP3A4CYP26A1
SCHEMBL5898834 0.84 APP (0.43) RARBRARGRARACYP3A4CYP26A1
SCHEMBL4065062 0.80 APP (0.39) GRM5APPMAPT
SCHEMBL2763104 0.78 APP (0.32) CYP3A4APPMAPTKDM4EMEN1
SCHEMBL2187490 0.77 APP (0.36) RARAGRM5APPMAPTNPC1
SCHEMBL15232924 0.76
SCHEMBL2762889 0.75 GRIN2D (0.35) RARBRARGRARACYP3A4CYP26A1
SCHEMBL4055656 0.71 EPHX2 (0.34) GRM5APP
SCHEMBL2763071 0.69 APP (0.34) CYP3A4GRM5APPMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530596-B2 Polymer for forming insulating film, composition for forming insulating film, insulating film, and electronic device having same SUMITOMO BAKELITE CO., LTD. (JP) 2013-09-10 US disclosed
US-20100130672-A1 POLYMER FOR FORMING INSULATING FILM, COMPOSITION FOR FORMING INSULATING FILM, INSULATING FILM, AND ELECTRONIC DEVICE HAVING SAME SUMITOMO BAKELITE CO., LTD. (JP) 2010-05-27 US disclosed
EP-2177545-A1 POLYMER FOR FORMING INSULATING FILM, COMPOSITION FOR FORMING INSULATING FILM, INSULATING FILM, AND ELECTRONIC DEVICE HAVING INSULATING FILM Sumitomo Bakelite Company Limited (JP) 2010-04-21 EP disclosed