Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 8/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 8/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926749 | 0.89 | TBXA2R (0.54) | TBXA2RPTGDRS1PR1 | |
| SCHEMBL2925656 | 0.83 | TBXA2R (0.55) | TBXA2RPTGDRS1PR1 | |
| SCHEMBL27631943 | 0.80 | TBXA2R (0.40) | TBXA2RPTGDRPIK3C3 | |
| SCHEMBL1254300 | 0.78 | TBXA2R (0.39) | TBXA2RPTGDR | |
| SCHEMBL27710004 | 0.73 | PTGDR (0.43) | TBXA2RPTGDR | |
| SCHEMBL2922357 | 0.73 | PTGDR (0.44) | TBXA2RPTGDRS1PR1 | |
| SCHEMBL2923853 | 0.70 | PTGDR (0.53) | TBXA2RPTGDRS1PR1S1PR5 | |
| SCHEMBL2446502 | 0.69 | S1PR1 (0.46) | S1PR1S1PR5MIF | |
| SCHEMBL2446506 | 0.69 | S1PR1 (0.46) | S1PR1S1PR5MIF | |
| SCHEMBL2018070 | 0.66 | GAA (0.37) | S1PR1KDM4EALDH1A1HSD17B10MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1732171-A | Pyridopyrrolizine and pyridoindolizine derivatives | MERCK FROSST CANADA INC (CA) | 2006-02-08 | — | — | CN | disclosed |