Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.51 |
| ▸ | MAX | P61244 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15660519 | 0.87 | MYC (0.54) | MYCMAXRXRARXRBRXRG | |
| SCHEMBL2713307 | 0.86 | MRGPRX4 (0.49) | MYCRXRARXRBRXRGMRGPRX4 | |
| SCHEMBL28607405 | 0.84 | PTPN11 (0.51) | MYCMAXRXRARXRBRXRG | |
| SCHEMBL9623925 | 0.83 | POLB (0.55) | MYCMRGPRX4 | |
| SCHEMBL15662429 | 0.83 | MRGPRX4 (0.54) | MYCMAXRXRARXRBRXRG | |
| SCHEMBL4275354 | 0.83 | CA12 (0.67) | MYCMAXMRGPRX4 | |
| SCHEMBL10798892 | 0.83 | EP300 (0.56) | MYCMAXRXRARXRBRXRG | |
| SCHEMBL17908022 | 0.83 | TSHR (0.69) | MRGPRX4 | |
| SCHEMBL701512 | 0.81 | TSHR (0.68) | MRGPRX4TAS1R3TAS1R1 | |
| SCHEMBL2594977 | 0.80 | POLB (0.47) | MRGPRX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101619057-A | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARM INC | 2010-01-06 | — | — | CN | disclosed |
| CN-100509804-C | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARM INC (US) | 2009-07-08 | — | — | CN | disclosed |
| CN-1675201-A | N-substituted piperidine derivatives as serotonin receptor agents | ACADIA PHARM INC (US) | 2005-09-28 | — | — | CN | disclosed |