Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 2/20 | 0.48 |
| ▸ | MAX | P61244 | 2/20 | 0.48 |
| ▸ | EP300 | Q09472 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198908 | 0.91 | ALDH1A1 (0.59) | XDHRXRARXRBRXRGSLC22A12 | |
| SCHEMBL4284947 | 0.88 | ALDH1A1 (0.51) | XDHRXRARXRBRXRGSLC22A12 | |
| SCHEMBL4277471 | 0.84 | ABCB1 (0.52) | XDHSLC22A12ALDH1A1DHODH | |
| SCHEMBL4282168 | 0.84 | FOS (0.50) | XDHSLC22A12NR1H4ALDH1A1DHODH | |
| SCHEMBL27632253 | 0.84 | MYC (0.51) | XDHRXRARXRBRXRGMYC | |
| SCHEMBL4289803 | 0.83 | FOS (0.54) | XDHSLC22A12NR1H4ALDH1A1HIF1A | |
| SCHEMBL4275354 | 0.83 | CA12 (0.67) | MYCMAXTSHRLMNAMAPK1 | |
| SCHEMBL17908022 | 0.83 | TSHR (0.69) | DHODHTSHRLMNAMAPK1HTT | |
| SCHEMBL10798892 | 0.83 | EP300 (0.56) | XDHRXRARXRBRXRGMYC | |
| SCHEMBL2803337 | 0.83 | MYC (0.50) | XDHRXRARXRBRXRGMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110824067-B | Method for detecting genotoxic impurities in febuxostat | 天津药物研究院有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-118549571-A | Method for separating and measuring content of related substances in febuxostat tablet by adopting HPLC (high Performance liquid chromatography) | 广州汇元医药科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-115785018-A | Preparation method of febuxostat decarboxylated impurities | 湖北广济药业股份有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-110483441-B | Preparation method of febuxostat crystal form A with low impurity content | 迪嘉药业集团股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-114149383-A | Febuxostat impurity | 广东东阳光药业有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-114149383-A | Febuxostat impurity | 广东东阳光药业有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-114149383-A | Febuxostat impurity | 广东东阳光药业有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-109238801-B | Hemolytic agent for blood cell analysis | 武汉百合龙腾生物科技有限责任公司 | 2021-08-13 | — | — | CN | disclosed |