SCHEMBL2763246

SCHEMBL2763246

C[Si](C)(C)OP(=O)(C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2764472 0.80
SCHEMBL575501 0.70
SCHEMBL14661488 0.69 PGK1 (0.30)
SCHEMBL6902333 0.69
SCHEMBL31178353 0.68 TSHR (0.30)
SCHEMBL394297 0.68 TSHR (0.30)
SCHEMBL15754317 0.67 PGK1 (0.32)
SCHEMBL575290 0.67 TSHR (0.46)
SCHEMBL575683 0.66 PGK1 (0.32)
Lithium SCHEMBL30431097 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9163039-B2 Process for the preparation of bis(perfluoroalkyl)phosphinic acid anhydrides MERCK PATENT GMBH (DE) 2015-10-20 US disclosed
EP-2736913-B1 METHOD FOR PRODUCING BIS(PERFLUOROALKYL)PHOSPHINIC ACID ANHYDRIDES MERCK PATENT GMBH (DE) 2015-08-26 EP disclosed
US-8846628-B2 Oral formulations of cytidine analogs and methods of use thereof CELGENE CORPORATION (US) 2014-09-30 US disclosed
US-20140155649-A1 PROCESS FOR THE PREPARATION OF BIS(PERFLUOROALKYL)PHOSPHINIC ACID ANHYDRIDES MERCK PATENT GMBH (DE) 2014-06-05 US disclosed
EP-2736913-A1 METHOD FOR PRODUCING BIS(PERFLUOROALKYL)PHOSPHINIC ACID ANHYDRIDES Merck Patent GmbH (DE) 2014-06-04 EP disclosed
WO-2013013766-A1 METHOD FOR PRODUCING BIS(PERFLUOROALKYL)PHOSPHINIC ACID ANHYDRIDES MERCK PATENT GMBH (DE) 2013-01-31 WO disclosed
EP-2180002-B1 Method for producing onium salts with dialkyl phosphonate anions with low halogenide content MERCK PATENT GMBH (DE) 2012-12-26 EP disclosed
EP-2180002-A1 Method for producing onium salts with dialkyl phosphonate anions with low halogenide content Merck Patent GmbH (DE) 2010-04-28 EP disclosed
US-20090253914-A1 PROCESS FOR THE PREPARATION OF ONIUM SALTS WITH DIALKYLPHOSPHATE, DIALKYLPHOSPHINATE OR (O-ALKYL)ALKYL- OR ALKYLPHOSPHONATE ANIONS HAVING A LOW HALIDE CONTENT MERCK PATENT GMBH (DE) 2009-10-08 US disclosed
EP-1824866-A1 METHOD FOR PRODUCING ONIUM SALTS COMPRISING DIALKYLPHOSPHATE ANIONS, DIALKYLPHOSPHINATE ANIONS OR (O-ALKYL)-ALKYL ANIONS OR ALKYL-PHOSPHONATE ANIONS HAVING A LOW HALIDE CONTENT MERCK PATENT GmbH (DE) 2007-08-29 EP disclosed
WO-2006063655-A1 METHOD FOR PRODUCING ONIUM SALTS COMPRISING DIALKYLPHOSPHATE ANIONS, DIALKYLPHOSPHINATE ANIONS OR (O-ALKYL)-ALKYL ANIONS OR ALKYL-PHOSPHONATE ANIONS HAVING A LOW HALIDE CONTENT MERCK PATENT GMBH (DE) 2006-06-22 WO disclosed