Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MAX | P61244 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPD | P32754 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483587 | 0.89 | TRPV1 (0.38) | TRPV1MYCMAXGRM5P2RX1 | |
| SCHEMBL3985618 | 0.89 | TRPV1 (0.38) | TRPV1MYCMAXGRM5P2RX1 | |
| SCHEMBL27653479 | 0.88 | GRM5 (0.34) | GRM5SMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL27653486 | 0.88 | MEN1 (0.36) | GRM5P2RX1SMN1; SMN2POLBMAPT | |
| SCHEMBL1483688 | 0.83 | MAPT (0.36) | TRPV1SMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL12830116 | 0.83 | MAPT (0.36) | TRPV1SMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL1483686 | 0.83 | MAPT (0.36) | TRPV1SMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL5750568 | 0.82 | SIRT5 (0.39) | TRPV1GRM5P2RX1TRPM8TRPV4 | |
| SCHEMBL12829978 | 0.82 | SIRT5 (0.39) | TRPV1GRM5P2RX1TRPM8TRPV4 | |
| SCHEMBL1483289 | 0.82 | SIRT5 (0.39) | TRPV1GRM5P2RX1TRPM8TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1798739-A | 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators | NISSAN CHEMICAL IND LTD (JP) | 2006-07-05 | — | — | CN | disclosed |