SCHEMBL27633490

SCHEMBL27633490

O=Cc1cccc2c1ccc1c2ccc2c3ccccc3ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.58
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
HSD17B10 Q99714 3/20 0.50
CYP2A6 P11509 1/20 0.50
TSHR P16473 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
POLB P06746 2/20 0.49
PTPN1 P18031 2/20 0.49
PAX8 Q06710 1/20 0.48
LMNA P02545 3/20 0.48
THRB P10828 2/20 0.48
BLM P54132 1/20 0.48
ERN1 O75460 1/20 0.46
MAPK1 P28482 2/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
APEX1 P27695 1/20 0.44
PMP22 Q01453 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17384097 1.00 HPRT1 (0.58) HPRT1ALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL548120 1.00 HPRT1 (0.58) HPRT1ALDH1A1TDP1HSD17B10CYP2A6
Furan SCHEMBL28204424 0.89 HPRT1 (0.47) HPRT1ALDH1A1TDP1HSD17B10CYP2A6
Pyridine SCHEMBL28268794 0.88 HPRT1 (0.45) HPRT1ALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL9005 0.87 MEN1 (0.57) ALDH1A1TDP1HSD17B10CYP2A6TSHR
SCHEMBL35849993 0.87 MEN1 (0.57) ALDH1A1TDP1HSD17B10CYP2A6TSHR
SCHEMBL30363267 0.86 ALDH1A1 (0.54) HPRT1ALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL29470186 0.86 ALDH1A1 (0.54) HPRT1ALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL14236880 0.86 HPRT1 (0.52) HPRT1ALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL10625571 0.86 HSD17B10 (0.48) HPRT1ALDH1A1TDP1HSD17B10CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1789395-A Tibetan herb dracocephalum heterophyllum essential oil with bacteria inhibiting and/or killing functions UNIV LANZHOU (CN) 2006-06-21 CN disclosed