Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859496 | 0.78 | TDP1 (0.46) | ALDH1A1HPGD | |
| SCHEMBL3640883 | 0.76 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL10975691 | 0.75 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL28234038 | 0.75 | TP53 (0.46) | ALDH1A1CYP3A4HSD17B10HPGDTHRB | |
| SCHEMBL16483445 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL739930 | 0.73 | HTR2A (0.38) | SLC6A4 | |
| SCHEMBL30631648 | 0.73 | HTR2A (0.38) | SLC6A4 | |
| SCHEMBL3241808 | 0.73 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL3892252 | 0.73 | CYP3A4 (0.53) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL11850025 | 0.73 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1668303-B | Selective estrogen receptor modulators containing phenylsulfonyl groups | LILLY CO ELI | 2010-10-27 | — | — | CN | disclosed |
| CN-1668303-A | Selective estrogen receptor modulators containing phenylsulfonyl groups | LILLY CO ELI (US) | 2005-09-14 | — | — | CN | disclosed |