Benzene

Benzene

SCHEMBL27634286

CCc1nnnn1C(C)C.c1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
CYP2C19 P33261 4/20 0.40
CYP1A2 P05177 3/20 0.40
POLB P06746 2/20 0.40
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
MCOLN2 Q8IZK6 2/20 0.37
CNR2 P34972 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP2D6 P10635 1/20 0.35
GAA P10253 2/20 0.35
CASP1 P29466 1/20 0.35
TRPV1 Q8NER1 1/20 0.34
DAGLA Q9Y4D2 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
HPGD P15428 1/20 0.33
HCAR3 P49019 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4408287 0.94 ALDH1A1 (0.51) ALDH1A1CYP2C19CYP1A2POLBCYP3A4
SCHEMBL4405441 0.78 CNR2 (0.52) ALDH1A1CYP2C19CYP1A2CYP3A4CYP2C9
SCHEMBL4409109 0.78 ALDH1A1 (0.49) ALDH1A1CYP2C19CYP1A2POLBCYP3A4
SCHEMBL7089605 0.75 ALDH1A1 (0.50) ALDH1A1CYP2C19CYP1A2POLBCYP3A4
SCHEMBL4413524 0.75 ALDH1A1 (0.50) ALDH1A1CYP2C19CYP1A2POLBCYP3A4
SCHEMBL11175358 0.75 ALDH1A1 (0.50) ALDH1A1CYP2C19CYP1A2POLBCYP3A4
SCHEMBL4405841 0.74 ALDH1A1 (0.46) ALDH1A1CYP2C19CYP1A2POLBTDP1
SCHEMBL4408572 0.73 ALDH1A1 (0.45) ALDH1A1CYP2C19CYP1A2POLBTDP1
SCHEMBL1779637 0.72 ALDH1A1 (0.47) ALDH1A1CYP2C19CYP1A2POLBCYP3A4
SCHEMBL10671615 0.72 ALDH1A1 (0.41) ALDH1A1CYP2C19CYP1A2POLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100402508-C Alkoxytetrazol-1-ylbenzaldehyde compound and process for producing the same TOYO KASEI KOGYO CO LTD (JP) 2008-07-16 CN disclosed
CN-1826329-A Alkoxy- (tetrazol-1-yl) benzaldehyde compound and process for producing the same TOYO KASEI KOGYO CO LTD (JP) 2006-08-30 CN disclosed