SCHEMBL27634397

SCHEMBL27634397

Cc1ccc(N(C)c2ccc3c(c2)-c2ccc(Nc4ccccc4)cc2C3)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.45
HPGD P15428 2/20 0.45
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CYP1A2 P05177 4/20 0.39
ADRA2A P08913 1/20 0.39
MAOA P21397 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2C P28335 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR2B P41595 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CYP3A4 P08684 3/20 0.38
APP P05067 2/20 0.38
MAPK14 Q16539 2/20 0.38
NR3C2 P08235 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SLC1A3 P43003 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27633770 0.84 HPGD (0.42) HSD17B10HPGDMAPTSMN1; SMN2CYP1A2
SCHEMBL29068489 0.83 HTT (0.49) HSD17B10HPGDMAPTSMN1; SMN2CYP1A2
SCHEMBL29068539 0.81 MAPT (0.40) HSD17B10HPGDMAPTSMN1; SMN2CYP1A2
SCHEMBL22588929 0.81 METAP1 (0.40) HSD17B10HPGDMAPTSMN1; SMN2CYP1A2
SCHEMBL7867939 0.80 CYP1A2 (0.44) HSD17B10HPGDMAPTSMN1; SMN2CYP1A2
SCHEMBL9516533 0.79 HPGD (0.72) HSD17B10HPGDMAPTCYP1A2SLC6A2
SCHEMBL13174486 0.79 APP (0.51) HSD17B10HPGDMAPTSMN1; SMN2CYP1A2
SCHEMBL9818058 0.78 KDM1A (0.41) HSD17B10HPGDMAPTSMN1; SMN2CYP1A2
SCHEMBL10405796 0.78 KDM1A (0.41) HSD17B10HPGDMAPTSMN1; SMN2CYP1A2
SCHEMBL7168804 0.78 HSD17B10 (0.54) HSD17B10HPGDMAPTSMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100449732-C Dicing die-bonding film NITTO DENKO CORP (JP) 2009-01-07 CN disclosed
CN-1670942-A Dicing die-bonding film NITTO DENKO CORP (JP) 2005-09-21 CN disclosed