SCHEMBL9516533

SCHEMBL9516533

Cc1ccc(N(C)c2ccc(Nc3ccc(Nc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.72
ALDH1A1 P00352 5/20 0.52
L3MBTL1 Q9Y468 4/20 0.52
HSD17B10 Q99714 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
ALOX12 P18054 3/20 0.52
TSHR P16473 3/20 0.52
ALOX15 P16050 2/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52
MAPK1 P28482 1/20 0.52
PTGS2 P35354 1/20 0.52
HTR2B P41595 1/20 0.52
GAA P10253 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NR3C2 P08235 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27315184 0.92 ALDH1A1 (0.62) HPGDALDH1A1L3MBTL1HSD17B10TDP1
SCHEMBL17753331 0.91 HPGD (0.59) HPGDALDH1A1L3MBTL1HSD17B10TDP1
SCHEMBL9782622 0.90 ALDH1A1 (0.59) HPGDALDH1A1L3MBTL1HSD17B10TDP1
SCHEMBL9513157 0.87 NR3C2 (0.60) HPGDALDH1A1L3MBTL1HSD17B10TDP1
SCHEMBL23373800 0.86 HPGD (0.50) HPGDALDH1A1L3MBTL1TDP1TSHR
SCHEMBL4893330 0.86 HPGD (0.75) HPGDALDH1A1L3MBTL1HSD17B10TDP1
Diphenylamine SCHEMBL2721122 0.85 HSD17B10 (0.60) HPGDALDH1A1L3MBTL1HSD17B10TDP1
SCHEMBL9461706 0.85 HPGD (1.00) HPGDALDH1A1L3MBTL1HSD17B10TDP1
SCHEMBL172875 0.85 HPGD (1.00) HPGDALDH1A1L3MBTL1HSD17B10TDP1
SCHEMBL24137168 0.85 HPGD (1.00) HPGDALDH1A1L3MBTL1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273418-B1 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MFG CO LTD (JP) 1993-11-24 EP disclosed
US-4803193-A COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-02-07 US disclosed
EP-0273418-A2 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-07-06 EP disclosed