Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 19/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1780415 | 0.76 | RIPK1 (0.50) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL1778230 | 0.69 | RIPK1 (0.55) | RIPK1HRH4HRH3 | |
| SCHEMBL1777072 | 0.69 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL1777920 | 0.69 | RIPK1 (0.44) | RIPK1HRH4HRH3 | |
| SCHEMBL12606193 | 0.69 | RIPK1 (0.54) | RIPK1 | |
| SCHEMBL1779175 | 0.69 | RIPK1 (0.40) | RIPK1 | |
| SCHEMBL25781276 | 0.68 | RIPK1 (0.50) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL1779937 | 0.67 | HRH4 (0.58) | RIPK1HRH4HRH3 | |
| SCHEMBL1776687 | 0.67 | RIPK1 (0.45) | RIPK1HRH4HRH3 | |
| SCHEMBL12009940 | 0.67 | CHRM2 (0.50) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100509811-C | Azaindoles | AVENTIS PHARMA LTD (GB) | 2009-07-08 | — | — | CN | disclosed |
| CN-1665809-A | Azaindoles | AVENTIS PHARMA LTD (GB) | 2005-09-07 | — | — | CN | disclosed |