Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15763948 | 0.87 | CA1 (0.44) | CA1CA2CA9MMP2MMP3 | |
| SCHEMBL4138787 | 0.85 | CA2 (0.42) | CA1CA2CA9MMP2MMP3 | |
| SCHEMBL780159 | 0.80 | CA1 (0.48) | CA1CA2CA9MMP2MMP3 | |
| SCHEMBL19568048 | 0.79 | CA1 (0.47) | CA1CA2CA9MMP2MMP3 | |
| SCHEMBL28898180 | 0.79 | CA1 (0.47) | CA1CA2CA9MMP2MMP3 | |
| SCHEMBL12014821 | 0.78 | KMT2A (0.61) | CA1CA2CA9PPARGKMT2A | |
| SCHEMBL23395751 | 0.77 | KMT2A (0.47) | CA1CA2MMP2MMP3MMP9 | |
| SCHEMBL18631973 | 0.77 | CA1 (0.45) | CA1CA2CA9MMP2MMP3 | |
| SCHEMBL3742274 | 0.77 | CA1 (0.45) | CA1CA2CA9MMP2MMP3 | |
| SCHEMBL9451341 | 0.77 | CA2 (0.73) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1812984-A | Benzofuranyl-piperazinyl and benzothienyl-piperazinyl quinolines as 5-hydroxytryptamine reuptake inhibitors | WHETH CORP (US) | 2006-08-02 | — | — | CN | disclosed |