Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656015 | 1.00 | TARBP2 (0.50) | TARBP2CYP19A1MAPTTRPM8NPSR1 | |
| SCHEMBL4680961 | 0.91 | TARBP2 (0.58) | TARBP2CYP19A1MAPTTRPM8NPSR1 | |
| SCHEMBL4680307 | 0.88 | TARBP2 (0.54) | TARBP2CYP19A1MAPTTRPM8NPSR1 | |
| SCHEMBL4679991 | 0.88 | TARBP2 (0.54) | TARBP2CYP19A1MAPTTRPM8NPSR1 | |
| SCHEMBL27634889 | 0.85 | NR1H2 (0.39) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27656026 | 0.85 | NR1H2 (0.39) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5752570 | 0.82 | TARBP2 (0.52) | TARBP2CYP19A1MAPTTRPM8NPSR1 | |
| SCHEMBL14101238 | 0.81 | TARBP2 (0.56) | TARBP2CYP19A1MAPTTRPM8MEN1 | |
| SCHEMBL27655891 | 0.78 | CDH1 (0.41) | ALDH1A1DHODHCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27655901 | 0.78 | CDH1 (0.41) | ALDH1A1DHODHCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809554-A | 3-substituted 5,6-diaryl-pyrazine-2-carboxamide and -2-sulfonamide derivatives as cb1 modulators | ASTRAZENECA AB (SE) | 2006-07-26 | — | — | CN | disclosed |