Acetoacetic Acid

Acetoacetic Acid

SCHEMBL2763489

CC(=O)CC(=O)O.NC1C(=O)NC(=O)NC1=O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.38
LMNA P02545 1/20 0.36
TLR4 O00206 4/20 0.36
TSHR P16473 2/20 0.34
RGS12 O14924 1/20 0.34
KDM4E B2RXH2 2/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
HTT P42858 2/20 0.32
MAPT P10636 2/20 0.32
USP2 O75604 1/20 0.32
TP53 P04637 1/20 0.31
GAA P10253 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL664354 0.98 HSD17B10 (0.37) HSD17B10LMNATLR4TSHRRGS12
Acetic Acid SCHEMBL2763491 0.84 HSD17B10 (0.41) HSD17B10LMNATSHRRGS12HTT
Acetic Acid SCHEMBL1519511 0.82 HSD17B10 (0.39) HSD17B10LMNATSHRRGS12USP2
Acetic Acid SCHEMBL664355 0.76 CA1 (0.39) HSD17B10LMNATSHRRGS12
SCHEMBL131371 0.74 TSHR (0.39) HSD17B10LMNATSHRRGS12KDM4E
Acetoacetic Acid SCHEMBL21402364 0.69
Acetoacetic Acid SCHEMBL31420005 0.69
Acetoacetic Acid SCHEMBL10941648 0.69 LDHA (0.57) LMNATSHRKDM4EKDM6BKDM5C
Acetoacetic Acid SCHEMBL1406366 0.69 LDHA (0.57) LMNATSHRKDM4EKDM6BKDM5C
Acetoacetic Acid SCHEMBL1144213 0.69 LDHA (0.57) LMNATSHRKDM4EKDM6BKDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6261773-B1 WHICH INCLUDES ONE OR MORE COMPOUNDS SUCH AS ETHYLENEDIAMINETETRAACETIC ACID, NITRILOTRIACETIC ACID, URAMIL DIACETIC ACID, 1,2-CYCLOHEXANEDIAMINETETRAACETIC ACID, DIETHYLENETRIAMINEPENTAACETIC ACID, AND SALTS THEREOF TOYO BOSEKI KABUSHIKI KAISHA (JP) 2001-07-17 US claimed
US-6008170-A PROTEASE FOR REMOVING PROTEINS AND GUM ARABIC AS A HYDROPHILICITY RENDERING COMPONENT, REMOVING OR DEACTIVATING DIVALENT METAL IONS IN GUM ARABIC TOMEY TECHNOLOGY CORPORATION (JP) 1999-12-28 US claimed
US-11447821-B2 Nucleic acid amplification and testing CAMBRIDGE ENTERPRISE LIMITED (GB) 2022-09-20 US disclosed
EP-2115166-B1 NUCLEIC ACID AMPLIFICATION AND TESTING CAMBRIDGE ENTPR LTD (GB) 2022-05-11 EP disclosed
CN-107208365-B Printing agent, fabric and method for producing printing agent DIC株式会社 2020-09-15 CN disclosed
US-10704042-B2 Ligation-based RNA amplification GE HEALTHCARE BIO-SCIENCES CORP. (US) 2020-07-07 US disclosed
US-20200157617-A1 NUCLEIC ACID AMPLIFICATION AND TESTING CAMBRIDGE ENTERPRISE LIMITED (GB) 2020-05-21 US disclosed
US-10563254-B2 Nucleic acid amplification and testing CAMBRIDGE ENTERPRISE LIMITED (GB) 2020-02-18 US disclosed
US-20180320172-A1 LIGATION-BASED RNA AMPLIFICATION GLOBAL LIFE SCIENCES SOLUTIONS USA LLC 2018-11-08 US disclosed
CN-107208365-A The manufacture method of stamp agent, cloth and silk thing and stamp agent DIC株式会社 2017-09-26 CN disclosed
US-7772383-B2 Chemical PCR: Compositions for enhancing polynucleotide amplification reactions THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2010-08-10 US disclosed
JP-2004135571-A CELL-RELEASING AGENT AND METHOD FOR PRODUCING CELL SHEET SANYO CHEM IND LTD 2004-05-13 JP disclosed
US-20030039992-A1 Compositions and methods for enhancing polynucleotide amplification reactions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-02-27 US disclosed
US-6514330-B1 Copper phthalocyanine dyes/pigments, fungicides, antirusting agents and antiagglomerants, used for mechanical printing; complexing SEIKO EPSON CORPORATION (JP) 2003-02-04 US disclosed
WO-2002061137-A2 COMPOSITIONS AND METHODS FOR ENHANCING POLYNUCLEOTIDE AMPLIFICATION REACTIONS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2002-08-08 WO disclosed
US-6261773-B1 WHICH INCLUDES ONE OR MORE COMPOUNDS SUCH AS ETHYLENEDIAMINETETRAACETIC ACID, NITRILOTRIACETIC ACID, URAMIL DIACETIC ACID, 1,2-CYCLOHEXANEDIAMINETETRAACETIC ACID, DIETHYLENETRIAMINEPENTAACETIC ACID, AND SALTS THEREOF TOYO BOSEKI KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1043369-A1 Ink composition containing copper complex colorant SEIKO EPSON CORPORATION (JP) 2000-10-11 EP disclosed
EP-0125507-B1 INORGANIC COMPOSITE MATERIAL AND PROCESS FOR PREPARING THE SAME KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-08-17 EP disclosed
US-4668299-A Inorganic composite material and process for preparing the same KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-05-26 US disclosed
EP-0130575-A1 Electrically conductive fiber KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-01-09 EP disclosed