Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.69 |
| ▸ | BCL9 | O00512 | 4/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | PRCP | P42785 | 1/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27634943 | 1.00 | PPARA (0.69) | PPARABCL9CTNNB1SIGMAR1DRD4 | |
| SCHEMBL27616063 | 1.00 | PPARA (0.69) | PPARABCL9CTNNB1SIGMAR1DRD4 | |
| SCHEMBL4032456 | 0.83 | PPARA (0.75) | PPARABCL9CTNNB1ALDH1A1POLB | |
| SCHEMBL4028658 | 0.83 | PPARA (0.75) | PPARABCL9CTNNB1ALDH1A1POLB | |
| SCHEMBL4027306 | 0.83 | PPARA (0.75) | PPARABCL9CTNNB1ALDH1A1POLB | |
| SCHEMBL29319669 | 0.83 | PPARA (0.66) | PPARABCL9CTNNB1DRD4DRD3 | |
| SCHEMBL4030653 | 0.82 | PPARA (1.00) | PPARABCL9CTNNB1 | |
| SCHEMBL4030088 | 0.82 | PPARA (1.00) | PPARABCL9CTNNB1 | |
| SCHEMBL29402050 | 0.82 | PPARA (1.00) | PPARABCL9CTNNB1 | |
| SCHEMBL4029011 | 0.82 | PPARA (1.00) | PPARABCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100439337-C | Phenyl substituted piperidine compounds for use as PPAR activators | PFIZER PROD INC (US) | 2008-12-03 | — | — | CN | claimed |
| CN-1717389-A | Phenyl substituted piperidine compounds for use as PPAR activators | PFIZER PROD INC (US) | 2006-01-04 | — | — | CN | claimed |
| CN-100439337-C | Phenyl substituted piperidine compounds for use as PPAR activators | PFIZER PROD INC (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-1717389-A | Phenyl substituted piperidine compounds for use as PPAR activators | PFIZER PROD INC (US) | 2006-01-04 | — | — | CN | disclosed |