Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.66 |
| ▸ | BCL9 | O00512 | 11/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29319693 | 0.84 | BCL9 (0.54) | PPARABCL9CTNNB1ALDH1A1RAB9A | |
| SCHEMBL27634943 | 0.83 | PPARA (0.69) | PPARABCL9CTNNB1ALDH1A1POLB | |
| SCHEMBL27634993 | 0.83 | PPARA (0.69) | PPARABCL9CTNNB1ALDH1A1POLB | |
| SCHEMBL27616063 | 0.83 | PPARA (0.69) | PPARABCL9CTNNB1ALDH1A1POLB | |
| SCHEMBL4029011 | 0.79 | PPARA (1.00) | PPARABCL9CTNNB1 | |
| SCHEMBL4030088 | 0.79 | PPARA (1.00) | PPARABCL9CTNNB1 | |
| SCHEMBL30498765 | 0.79 | PPARA (1.00) | PPARABCL9CTNNB1 | |
| SCHEMBL4030653 | 0.79 | PPARA (1.00) | PPARABCL9CTNNB1 | |
| SCHEMBL29402050 | 0.79 | PPARA (1.00) | PPARABCL9CTNNB1 | |
| SCHEMBL4028658 | 0.77 | PPARA (0.75) | PPARABCL9CTNNB1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |