Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635111 | 1.00 | DGAT1 (0.60) | DGAT1CA2CA12CA14CA1 | |
| SCHEMBL27747511 | 0.90 | DGAT1 (0.50) | DGAT1CA2CA1TDP1 | |
| SCHEMBL27469425 | 0.81 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL1731211 | 0.81 | DGAT1 (0.60) | DGAT1CA2CA12CA14CA1 | |
| SCHEMBL28714854 | 0.78 | DGAT1 (0.44) | DGAT1MAOAMAOB | |
| SCHEMBL29908023 | 0.78 | DGAT1 (0.44) | DGAT1MAOAMAOB | |
| SCHEMBL27859821 | 0.78 | DGAT1 (0.44) | DGAT1CA2CA1 | |
| SCHEMBL1486198 | 0.78 | DGAT1 (0.44) | DGAT1CA2CA1 | |
| SCHEMBL27721975 | 0.78 | DGAT1 (0.44) | DGAT1CA2CA1 | |
| SCHEMBL31150303 | 0.77 | DGAT1 (0.45) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1812979-A | Substituted aminocarboxylic acids as inhibitors of protein tyrosine phosphatase-1B | INST PHARM DISCOVERY INC (US) | 2006-08-02 | — | — | CN | disclosed |