Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 3/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 5/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774700 | 0.83 | KMT2A (0.43) | STK17BSTK17AKMT2AMEN1ALDH1A1 | |
| SCHEMBL3447092 | 0.83 | KMT2A (0.50) | STK17BSTK17AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5151737 | 0.83 | STK17A (0.50) | STK17BSTK17AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5152648 | 0.80 | STK17B (0.45) | STK17BSTK17AKMT2AMEN1ALDH1A1 | |
| SCHEMBL3715848 | 0.80 | STK17A (0.61) | STK17BSTK17AKMT2AMEN1 | |
| SCHEMBL3448808 | 0.79 | MEN1 (0.47) | STK17BSTK17AKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5154810 | 0.79 | STK17A (0.60) | STK17BSTK17AKMT2AMEN1 | |
| SCHEMBL4188949 | 0.79 | KMT2A (0.47) | STK17BSTK17AKMT2AMEN1L3MBTL1 | |
| SCHEMBL30367077 | 0.79 | MEN1 (0.47) | STK17BSTK17AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5152523 | 0.79 | STK17B (0.44) | STK17BSTK17AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1717396-A | Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents | SCHERING AG (DE) | 2006-01-04 | — | — | CN | disclosed |