Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.42 |
| ▸ | BACE1 | P56817 | 6/20 | 0.42 |
| ▸ | GLI1 | P08151 | 2/20 | 0.40 |
| ▸ | GLI2 | P10070 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656299 | 1.00 | ADRB3 (0.42) | ADRB3ADRB1BACE1GLI1GLI2 | |
| SCHEMBL6244538 | 0.97 | BACE1 (0.43) | ADRB3ADRB1BACE1GLI1GLI2 | |
| SCHEMBL27635157 | 0.93 | GLI1 (0.47) | ADRB3ADRB1BACE1GLI1GLI2 | |
| SCHEMBL6239101 | 0.92 | BACE1 (0.43) | ADRB3ADRB1BACE1SLC2A1ADRB2 | |
| SCHEMBL4472057 | 0.92 | ADRB3 (0.45) | ADRB3ADRB1BACE1GLI1GLI2 | |
| SCHEMBL4472051 | 0.92 | ADRB3 (0.45) | ADRB3ADRB1BACE1GLI1GLI2 | |
| SCHEMBL27656169 | 0.92 | ADRB3 (0.46) | ADRB3ADRB1BACE1GLI1GLI2 | |
| SCHEMBL6541560 | 0.91 | BACE1 (0.40) | ADRB3ADRB1BACE1GLI1GLI2 | |
| SCHEMBL6541553 | 0.91 | BACE1 (0.40) | ADRB3ADRB1BACE1GLI1GLI2 | |
| SCHEMBL6541562 | 0.91 | BACE1 (0.40) | ADRB3ADRB1BACE1GLI1GLI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1802355-A | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-07-12 | — | — | CN | disclosed |