Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6244538 | 0.95 | BACE1 (0.43) | BACE1ADRB3ADRB1SLC2A1ADRB2 | |
| SCHEMBL27635239 | 0.92 | ADRB3 (0.42) | BACE1ADRB3ADRB1SLC2A1ADRB2 | |
| SCHEMBL27656299 | 0.92 | ADRB3 (0.42) | BACE1ADRB3ADRB1SLC2A1ADRB2 | |
| SCHEMBL27635157 | 0.91 | GLI1 (0.47) | BACE1ADRB3ADRB1 | |
| SCHEMBL4472057 | 0.90 | ADRB3 (0.45) | BACE1ADRB3ADRB1SLC2A1ADRB2 | |
| SCHEMBL4472051 | 0.90 | ADRB3 (0.45) | BACE1ADRB3ADRB1SLC2A1ADRB2 | |
| SCHEMBL27656169 | 0.90 | ADRB3 (0.46) | BACE1ADRB3ADRB1SLC2A1ADRB2 | |
| SCHEMBL6541562 | 0.89 | BACE1 (0.40) | BACE1ADRB3ADRB1SLC2A1ADRB2 | |
| SCHEMBL6541553 | 0.89 | BACE1 (0.40) | BACE1ADRB3ADRB1SLC2A1ADRB2 | |
| SCHEMBL6541560 | 0.89 | BACE1 (0.40) | BACE1ADRB3ADRB1SLC2A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546086-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004002939-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-08 | — | — | WO | disclosed |