Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391046 | 0.81 | MAPT (0.47) | MAPTSIGMAR1GAAGRM6TMEM97 | |
| SCHEMBL3604990 | 0.76 | MAPT (0.47) | MAPTGAAGRM6TMEM97LMNA | |
| SCHEMBL4401474 | 0.75 | MAPT (0.45) | MAPTSIGMAR1GRM6TMEM97OPRM1 | |
| SCHEMBL26620089 | 0.74 | GAA (0.59) | SIGMAR1GAAACHELMNA | |
| SCHEMBL2205566 | 0.73 | MAPT (0.43) | MAPTHRH2GRM6TMEM97 | |
| SCHEMBL21057421 | 0.72 | MAPT (0.45) | MAPTSIGMAR1GAAGRM6TMEM97 | |
| SCHEMBL4395795 | 0.72 | MAPT (0.42) | MAPTHRH2SIGMAR1GRM6TMEM97 | |
| SCHEMBL22525231 | 0.72 | MAPT (0.46) | MAPTGRM6ACHELMNA | |
| SCHEMBL21563539 | 0.72 | MAPT (0.46) | MAPTGRM6ACHELMNA | |
| SCHEMBL24802004 | 0.71 | MAPT (0.44) | MAPTSIGMAR1GAATMEM97ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1688527-A | Fused benzene derivatives and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-10-26 | — | — | CN | disclosed |