⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276355 | 1.00 | — | — | |
| SCHEMBL19415072 | 0.69 | — | — | |
| SCHEMBL25883415 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL25673206 | 0.67 | — | — | |
| SCHEMBL4528380 | 0.67 | — | — | |
| SCHEMBL19382309 | 0.67 | ALDH1A1 (0.37) | — | |
| SCHEMBL13977709 | 0.67 | — | — | |
| SCHEMBL28661541 | 0.67 | — | — | |
| SCHEMBL14207291 | 0.67 | — | — | |
| SCHEMBL25388030 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134013-B2 | Amide compound and thrombopoietin receptor activator | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-13 | — | — | US | disclosed |
| US-20090131659-A1 | AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-05-21 | — | — | US | disclosed |