Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15158 | 0.83 | LMNA (0.40) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL17857948 | 0.82 | LMNA (0.39) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| Lithium SCHEMBL30307090 | 0.81 | LMNA (0.39) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| Iodide SCHEMBL29831346 | 0.81 | LMNA (0.39) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28286046 | 0.81 | LMNA (0.40) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL25250816 | 0.81 | LMNA (0.39) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL30988127 | 0.81 | KMT2A (0.41) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL28310329 | 0.81 | LMNA (0.39) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| Hydrogen Sulfide SCHEMBL28313413 | 0.81 | LMNA (0.39) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6466101 | 0.81 | TRPV1 (0.42) | HPGDSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100418973-C | Process for preparing acylphosphanes and derivatives thereof | CIBA SC HOLDING AG (CH) | 2008-09-17 | — | — | CN | disclosed |
| CN-1823077-A | Process for preparing acylphosphines and their derivatives | CIBA SC HOLDING AG (CH) | 2006-08-23 | — | — | CN | disclosed |