Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | AOC1 | P19801 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258486 | 0.88 | HIF1A (0.44) | HRH3HIF1AEPAS1KMT2A | |
| SCHEMBL7493066 | 0.78 | HIF1A (0.39) | HIF1AEPAS1KMT2A | |
| SCHEMBL193417 | 0.73 | — | — | |
| SCHEMBL4034786 | 0.71 | — | — | |
| SCHEMBL28319712 | 0.71 | — | — | |
| SCHEMBL14333827 | 0.68 | HCAR2 (0.34) | HIF1AEPAS1KMT2A | |
| Dimethylformamide SCHEMBL27681028 | 0.67 | TSHR (0.43) | HRH3HRH4CYP3A4AOC1MEN1 | |
| SCHEMBL14335170 | 0.65 | TSHR (0.46) | HIF1AEPAS1KMT2A | |
| SCHEMBL5789575 | 0.65 | NPC1 (0.33) | KMT2A | |
| SCHEMBL6251513 | 0.65 | HRH3 (0.38) | HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871745-B1 | PREPARATION OF 2-SUBSTITUTED 4-CHLORO-5-FORMYLIMIDAZOLES BY VILSMEIER REACTION OF THE CONDENSATION PRODUCT OF GLYCINE AND AN IMIDO ESTER WITH A FORMAMIDE IN THE PRESENCE OF A TRIFLATE (TRIFLUORMETHANESULPHONATE) CATALYST | DISHMAN PHARMACEUTICALS AND CH (IN) | 2010-10-20 | — | — | EP | claimed |