⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319712 | 0.97 | — | — | |
| Dimethylformamide SCHEMBL27681028 | 0.87 | TSHR (0.43) | — | |
| Tetrahydrofuran SCHEMBL27483025 | 0.84 | KDM4E (0.41) | — | |
| SCHEMBL4965314 | 0.77 | — | — | |
| SCHEMBL19361933 | 0.74 | — | — | |
| SCHEMBL11469459 | 0.74 | — | — | |
| SCHEMBL543476 | 0.74 | — | — | |
| SCHEMBL2763559 | 0.73 | HRH3 (0.44) | — | |
| SCHEMBL1997770 | 0.70 | — | — | |
| Cis-Urocanic Acid SCHEMBL1136889 | 0.69 | CYP3A4 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617889-B1 | Polymers for use as anion exchange membranes | ENVISION ENERGY USA LTD. (US) | 2026-05-05 | — | — | US | claimed |
| CN-111909098-A | hexahydro-5H-benzo [ d ] imidazole-5-ketone derivative and preparation method and application thereof | 深圳职业技术学院 | 2020-11-10 | — | — | CN | claimed |
| CN-110124525-B | Mixed matrix membrane containing imidazole ester metal organic framework material, preparation and application | 华中科技大学 | 2020-05-19 | — | — | CN | claimed |
| CN-106967213-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2019-11-05 | — | — | CN | claimed |
| CN-110124525-A | Mixed substrate membrane containing nano-grade molecular sieve and preparation and application containing imidazate metal-organic framework materials | 华中科技大学 | 2019-08-16 | — | — | CN | claimed |
| CN-110023311-A | Amino-naphtho- [1,2-d] imidazoles -5- ketone compounds or its pharmaceutically acceptable salt that 2- replaces | 生物电子技术有限公司 | 2019-07-16 | — | — | CN | claimed |
| CN-109771650-A | The composition being made of rush histamine release object and two substituted biphenyl derivatives | 黄泳华 | 2019-05-21 | — | — | CN | claimed |
| CN-108864047-A | A kind of preparation method of non-peptide batroxobin inhibitor dabigatran etcxilate | 河南师范大学 | 2018-11-23 | — | — | CN | claimed |
| EP-1900393-B1 | Hydrogen peroxide activation with diones and imidazoles | HENKEL AG & CO KGAA (DE) | 2018-02-28 | — | — | EP | claimed |
| CN-105992763-A | Neprilysin inhibitors | 施万生物制药研发IP有限责任公司 | 2016-10-05 | — | — | CN | claimed |
| EP-1114822-A2 | Indoles and tetrahydroisoquinolines containing alpha-keto oxadiazoles as serine protease inhibitors | Cortech Inc. (US) | 2001-07-11 | — | — | EP | claimed |
| EP-1093368-A1 | INDOLE AND TETRAHYDROISOQUINOLINE CONTAINING $g(a)-KETO OXADIAZOLES AS SERINE PROTEASE INHIBITORS | Cortech Inc. (US) | 2001-04-25 | — | — | EP | claimed |
| US-6100238-A | USEFUL AS INHIBITORS OF HUMAN NEUTROPHIL ELASTASE (HNE) FOR THE TREATMENT OF HNE-MEDIATED PROCESSES IMPLICATED IN CONDITIONS SUCH AS ADULT RESPIRATORY DISTRESS SYNDROME, SEPTIC SHOCK AND MULTIPLE ORGAN FAILURE | CORTECH INC. (US) | 2000-08-08 | — | — | US | claimed |
| WO-1999062514-A1 | INDOLE AND TETRAHYDROISOQUINOLINE CONTAINING α-KETO OXADIAZOLES AS SERINE PROTEASE INHIBITORS | CORTECH INC. (US) | 1999-12-09 | — | — | WO | claimed |
| WO-1999051598-A1 | SUBSTITUTED 9H-PYRIDINO[2,3-b]INDOLE AND 9H-PYRIMIDINO[4,5-b]INDOLE DERIVATIVES: SELECTIVE NEUROPEPTIDE y RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 1999-10-14 | — | — | WO | claimed |
| EP-0647640-B1 | Process for the preparation of pilocarpine derivatives | MERCK PATENT GMBH (DE) | 1999-03-24 | — | — | EP | claimed |
| US-5530136-A | HIGH YIELD; BY-PRODUCT INHIBITION | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-06-25 | — | — | US | claimed |
| EP-0647640-A1 | Process for the preparation of pilocarpine derivatives | MERCK PATENT GmbH (DE) | 1995-04-12 | — | — | EP | claimed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | claimed |
| US-4977272-A | Radiation absorbers | THE STANDARD OIL COMPANY (US) | 1990-12-11 | — | — | US | claimed |