Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 4/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28802581 | 0.83 | APLNR (0.37) | APLNRDGAT1OPRM1KDM1AKDM1B | |
| SCHEMBL30169618 | 0.83 | APLNR (0.50) | APLNRDGAT1OPRM1KDM1APDE2A | |
| SCHEMBL2550576 | 0.83 | APLNR (0.50) | APLNRDGAT1OPRM1KDM1APDE2A | |
| SCHEMBL31690066 | 0.81 | APLNR (0.49) | APLNRDGAT1OPRM1KDM1APDE2A | |
| SCHEMBL16104803 | 0.81 | APLNR (0.49) | APLNRDGAT1OPRM1KDM1APDE2A | |
| SCHEMBL15861423 | 0.81 | APLNR (0.49) | APLNRDGAT1OPRM1KDM1APDE2A | |
| SCHEMBL3988011 | 0.79 | APLNR (0.47) | APLNRDGAT1OPRM1KDM1APDE2A | |
| SCHEMBL701193 | 0.79 | PDE2A (0.56) | APLNRDGAT1OPRM1KDM1APDE2A | |
| SCHEMBL16043191 | 0.79 | PDE2A (0.56) | APLNRDGAT1OPRM1KDM1APDE2A | |
| SCHEMBL9947727 | 0.79 | PDE2A (0.56) | APLNRDGAT1OPRM1KDM1APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1832922-A | Sulfonyl-substituted N- (biarylmethyl) aminocyclopropanecarboxamides | MERCK & CO INC (US) | 2006-09-13 | — | — | CN | disclosed |