Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.88 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.58 |
| ▸ | TACR1 | P25103 | 6/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.57 |
| ▸ | ITGAL | P20701 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635939 | 1.00 | PPARG (0.88) | PPARGMEN1KMT2AGPR132MRGPRX4 | |
| SCHEMBL27656942 | 0.90 | PPARG (0.75) | PPARGMEN1KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL27656944 | 0.90 | PPARG (0.75) | PPARGMEN1KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL23097226 | 0.89 | PPARG (0.73) | PPARGMEN1KMT2ATACR1HSP90AA1 | |
| SCHEMBL22892483 | 0.89 | PPARG (0.73) | PPARGMEN1KMT2ATACR1HSP90AA1 | |
| SCHEMBL29400386 | 0.89 | PPARG (0.73) | PPARGMEN1KMT2ATACR1HSP90AA1 | |
| SCHEMBL28715267 | 0.89 | PPARG (0.73) | PPARGMEN1KMT2ATACR1HSP90AA1 | |
| SCHEMBL22091570 | 0.88 | PPARG (0.72) | PPARGMEN1KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL22091569 | 0.88 | PPARG (0.72) | PPARGMEN1KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL27656943 | 0.88 | PPARG (0.72) | PPARGMEN1KMT2AHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100361973-C | Benzyloxy-substituted tryptophan derivative, its analogs, production and use thereof | UNIV FUDAN (CN) | 2008-01-16 | — | — | CN | disclosed |
| CN-1817861-A | Benzyloxy-substituted tryptophan derivative, its analogs, production and use thereof | UNIV FUDAN (CN) | 2006-08-16 | — | — | CN | disclosed |