SCHEMBL27636503

SCHEMBL27636503

O=C(c1ccc(Br)cc1S(=O)(=O)Nc1cccc2nccnc12)N1CCOCC1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27636524 0.91 CCKBR (0.79) CCKBR
SCHEMBL27657442 0.91 CCKBR (0.79) CCKBR
SCHEMBL27636488 0.89 CCKBR (0.80) CCKBR
SCHEMBL27657478 0.89 CCKBR (0.66) CCKBR
SCHEMBL27636478 0.89 CCKBR (0.80) CCKBR
SCHEMBL1381588 0.89 CCKBR (1.00) CCKBR
SCHEMBL27639529 0.86 CCKBR (0.66) CCKBR
SCHEMBL27657449 0.86 CCKBR (0.70) CCKBR
SCHEMBL27636584 0.85 CCKBR (0.69) CCKBR
SCHEMBL27657460 0.85 CCKBR (0.69) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1863781-A 2- (quinoxalin-5-ylsulfonamido) -benzamide compounds as cholecystokinin 2 modulators JANSSEN PHARMACEUTICA NV (BE) 2006-11-15 CN claimed
CN-1863781-A 2- (quinoxalin-5-ylsulfonamido) -benzamide compounds as cholecystokinin 2 modulators JANSSEN PHARMACEUTICA NV (BE) 2006-11-15 CN disclosed
CN-1863782-A 2-(quinoxalin-5-ylsulfonylamino)-benzamide compounds as cck2 modulators JANSSEN PHARMACEUTICA NV (BE) 2006-11-15 CN disclosed