Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 5/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887204 | 0.90 | SCN2A (0.47) | SCN2ANPY5RMAPTKDM4EMEN1 | |
| SCHEMBL6887052 | 0.90 | SCN2A (0.47) | SCN2ANPY5RMAPTKDM4EMEN1 | |
| SCHEMBL6027412 | 0.84 | SCN2A (0.42) | SCN2ANPY5RMAPTKDM4EMEN1 | |
| SCHEMBL6027409 | 0.81 | NQO2 (0.46) | TRPV1SCN3ASCN9ANQO2 | |
| SCHEMBL6887198 | 0.81 | PTPN1 (0.54) | MAPTKDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL6028361 | 0.81 | PTPN1 (0.54) | MAPTKDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL6887046 | 0.81 | PTPN1 (0.54) | MAPTKDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL6028360 | 0.72 | PTPN1 (0.62) | MAPTKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL14311202 | 0.72 | PTPN1 (0.62) | MAPTKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL14305032 | 0.72 | PTPN1 (0.62) | MAPTKDM4EALDH1A1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1826111-A | Imidazole derivatives for treatment of allergic and hyperproliferative disorders | AVANIR PHARMACEUTICALS (US) | 2006-08-30 | — | — | CN | disclosed |