Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887046 | 1.00 | PTPN1 (0.54) | PTPN1PTPN2SCN3ASCN9AHPGD | |
| SCHEMBL6028361 | 1.00 | PTPN1 (0.54) | PTPN1PTPN2SCN3ASCN9AHPGD | |
| SCHEMBL6028790 | 0.93 | PTPN1 (0.62) | PTPN1PTPN2SCN3ASCN9AHPGD | |
| SCHEMBL14311202 | 0.93 | PTPN1 (0.62) | PTPN1PTPN2SCN3ASCN9AHPGD | |
| SCHEMBL14305032 | 0.93 | PTPN1 (0.62) | PTPN1PTPN2SCN3ASCN9AHPGD | |
| SCHEMBL6028360 | 0.93 | PTPN1 (0.62) | PTPN1PTPN2SCN3ASCN9AHPGD | |
| SCHEMBL6028629 | 0.87 | PTPN1 (0.50) | PTPN1PTPN2SCN3ASCN9AHPGD | |
| SCHEMBL6027061 | 0.87 | PTPN1 (0.50) | PTPN1PTPN2SCN3ASCN9AHPGD | |
| SCHEMBL6887204 | 0.87 | SCN2A (0.47) | KDM4EALDH1A1HSD17B10POLBMAPK1 | |
| SCHEMBL6887052 | 0.87 | SCN2A (0.47) | KDM4EALDH1A1HSD17B10POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229927-A1 | Imidazole derivatives for treatment of allergic and hyperproliferative disorders | AVANIR PHARMACEUTICALS | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229927-A1 | Imidazole derivatives for treatment of allergic and hyperproliferative disorders | ICOS, TSLP, IKZF3 | PTPN1 2513/4885PTPN2 2100/4885SCN3A 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.