Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL31166704 | 0.94 | — | — | |
| Bicarbonate SCHEMBL29039318 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL31588878 | 0.94 | — | — | |
| Bicarbonate SCHEMBL30995237 | 0.94 | — | — | |
| Bicarbonate SCHEMBL14563499 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL40504 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL27526 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14562750 | 0.89 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14562660 | 0.89 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14562672 | 0.89 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192587-A | Synergistic flame retardant based on lanthanum cerium tetravalent composite salt and preparation method thereof | 嘉兴大学 | 2025-06-24 | — | — | CN | claimed |
| CN-119082557-A | High-heat-conductivity high-strength aluminum alloy material and preparation method thereof | 哈尔滨宏源铝业有限责任公司 | 2024-12-06 | — | — | CN | claimed |
| CN-118702136-A | Small-particle-size hexagonal lanthanum cerium precursor and preparation method thereof | 甘肃稀土新材料股份有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118290973-A | Rare earth doped yttrium zirconium oxide spray material, and preparation method and application of coating | 包头稀土研究院 | 2024-07-05 | — | — | CN | claimed |
| CN-117866535-A | Preparation method and application of nano polishing powder suitable for optical glass chemical mechanical polishing and industrial production | 内蒙古师范大学 | 2024-04-12 | — | — | CN | claimed |
| CN-117486225-A | Low-viscosity rare earth aluminosilicate and preparation method and application thereof | 天津包钢稀土研究院有限责任公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117466634-A | Rare earth modified mullite and cordierite composite material and preparation method thereof | 包头市安德窑炉科技有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-117229041-B | Method for preparing light ceramsite by using rare earth halide solution modifier | 天津包钢稀土研究院有限责任公司 | 2024-01-30 | — | — | CN | claimed |
| CN-117229041-A | Method for preparing light ceramsite by using rare earth halide solution modifier | 天津包钢稀土研究院有限责任公司 | 2023-12-15 | — | — | CN | claimed |
| CN-115321578-B | Nano sphere-like rare earth fluoride polishing powder and preparation method thereof | 内蒙古科技大学 | 2023-09-19 | — | — | CN | claimed |
| CN-104371554-B | Fluorine cerium lanthanum oxide rare earth polishing | 乐山东承新材料有限公司 | 2017-07-11 | — | — | CN | claimed |
| CN-106675417-A | Spherical lanthanum cerium oxyfluoride rare earth polishing liquid and preparation method thereof | 安徽中创电子信息材料有限公司 | 2017-05-17 | — | — | CN | claimed |
| CN-106566416-A | Polishing liquid for Hetian jade | 扬州翠佛堂珠宝有限公司 | 2017-04-19 | — | — | CN | claimed |
| CN-104673098-B | Preparation technique of cerium-oxide-base rare-earth polishing powder | 安阳工学院 | 2017-01-18 | — | — | CN | claimed |
| CN-106268925-A | A kind of alkylation of toluene methanol xylol catalyst, Preparation Method And The Use | 中国石油大学(北京) | 2017-01-04 | — | — | CN | claimed |
| CN-106281042-A | The preparation method of modified cerium-based rare earth polishing powder | 包头海亮科技有限责任公司 | 2017-01-04 | — | — | CN | claimed |
| CN-104387988-B | A kind of preparation method of ultra-fine fluorine-containing cerium based relief polishing powder | 包头市金蒙研磨材料有限责任公司 | 2016-09-28 | — | — | CN | claimed |
| CN-105860826-A | Surface conditioning agent and adhesive membrane | 深圳市堃琦鑫华股份有限公司 | 2016-08-17 | — | — | CN | claimed |
| CN-104356947-B | Secondary intermediate is prepared method and is produced polishing powder from rare earth | 海城海美抛光材料制造有限公司 | 2016-07-06 | — | — | CN | claimed |
| CN-104449400-B | Corn shape nano lanthanum oxide cerium/Graphene compound rare-earth polishing powder and preparation method | 郑州轻工业学院 | 2016-06-29 | — | — | CN | claimed |