Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5052082 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL5502882 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8917975 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6691301 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21925452 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3337412 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14562723 | 0.94 | — | — | |
| Bicarbonate SCHEMBL372448 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL7649902 | 0.94 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL919437 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6193 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121850636-B | High-density CMA refractory material and preparation method thereof | Zhengzhou University Luoyang Industrial Technology Research Institute (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122091517-A | Carbon-coated lithium iron manganese phosphate positive electrode material, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-121754955-B | Integrated extraction and oil removal equipment and oil-free cerium carbonate preparation process | BAOTOU XINYUAN RARE EARCH HI-TECH NEW MATERIAL Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122079487-A | High-gloss antibacterial ceramic color glaze and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-224270742-U | Tail gas treatment device in praseodymium neodymium metal production | BAOTOU RARE EARTH HUAXING TECHNOLOGY Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| US-20260139143-A1 | ALKALINE CERIUM-BASED CR/P/F-FREE COATING COMPOSITION FOR METAL SURFACE PRE-TREATMENT | HENKEL AG & CO KGAA (DE) | 2026-05-21 | — | — | US | claimed |
| EP-4532102-B1 | METAL-SUPPORTED CATALYTIC SYSTEMS FOR METHANE COMBUSTION UNDER WET CONDITIONS, PROCESS FOR THEIR PREPARATION AND USES THEREOF | UMICORE AG & CO KG (DE) | 2026-05-20 | — | — | EP | claimed |
| CN-121790374-B | Carbon nitride coated sodium manganese pyrophosphate based positive electrode material, preparation method and application | 江苏隐功科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-117619391-B | Catalyst for synthesizing ammonia by using plasmas as well as preparation method and application of catalyst | 重庆大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122011825-A | Rare earth doped composite solid solution energy-saving coating and preparation method thereof | 包头市安德稀耐新材料有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-0203525-A1 | Catalyst for purifying exhaust gas | Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) | 1986-12-03 | — | — | EP | claimed |
| US-4546068-A | AROMATIC AMINE DEVELOPER, MANANESE AND OR CERIUM SALT, DIPHOSPHONIC ACID SEQUESTERING AGENT | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-10-08 | — | — | US | claimed |
| US-4468526-A | Process for the preparation of thiuram disulfides | AKZONA INCORPORATED (US) | 1984-08-28 | — | — | US | claimed |
| US-4459424-A | SECONDARY AMINE, CARBON DISULFIDE, METAL CONTAINING CATALYST | AKZONA INCORPORATED (US) | 1984-07-10 | — | — | US | claimed |
| US-4294726-A | Catalyst for the purification of exhaust gases of internal combustion engines | DEUTSCHE GOLD-UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-10-13 | — | — | US | claimed |
| US-4239656-A | PLATINUM OR PALLADIUM ON MAGNESIUM ALUMINATE SPINEL CONTAINING CERIA | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 1980-12-16 | — | — | US | claimed |
| US-4211882-A | OXIDIZING P-TOLUALDEHYDE, CATALYST CONSISTING OF A MANGANESE COMPOUND, A COBALT COMPOUND, A BROMINE COMPOUND, AND A NICKEL, IRON, CHROMIUM, OR LANTHANIDE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-07-08 | — | — | US | claimed |
| US-4126807-A | Gas discharge display device containing source of lanthanum series material in dielectric layer of envelope structure | OWENS-ILLINOIS, INC. (US) | 1978-11-21 | — | — | US | claimed |
| US-4110300-A | POLYSILOXANE, SILICA, PLATINUM OR COMPOUND, IRON SESQUIOXIDE | TORAY SILICONE COMPANY, LTD. (JP) | 1978-08-29 | — | — | US | claimed |
| US-4049463-A | Method for producing a pure cerium oxide | TREIBACHER CHEMISCHE WERKE AKTIENGESELLSCHAFT (OE) | 1977-09-20 | — | — | US | claimed |