Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092410 | 0.95 | FFAR1 (0.53) | SGMS2FFAR1KIFC1 | |
| SCHEMBL27638080 | 0.93 | FFAR1 (0.50) | SGMS2CAPN1FFAR1KMT2A | |
| SCHEMBL6182302 | 0.84 | SMN1; SMN2 (0.58) | NPC1MAPTFFAR1ALDH1A1 | |
| SCHEMBL27871429 | 0.84 | SMN1; SMN2 (0.58) | NPC1MAPTFFAR1ALDH1A1 | |
| SCHEMBL5927406 | 0.84 | LRRK2 (0.49) | LMNAFFAR1ALDH1A1KIFC1 | |
| SCHEMBL27658918 | 0.81 | GPR132 (0.64) | FFAR1KMT2A | |
| SCHEMBL5927212 | 0.81 | FFAR1 (0.56) | NPC1FFAR1 | |
| SCHEMBL27658913 | 0.80 | GPR132 (0.65) | MEN1KMT2A | |
| SCHEMBL27658922 | 0.78 | GPR132 (0.62) | FFAR1KMT2A | |
| SCHEMBL5926998 | 0.78 | LRRK2 (0.49) | LMNAALDH1A1KIFC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | claimed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |