SCHEMBL27638081

SCHEMBL27638081

O=C(NC(Cc1ccc(OCc2ccccc2)cc1)C(=O)O)c1cccc(OCc2cccc(OCc3ccccc3)c2)c1

nearest known ligand 0.89

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR132 Q9UNW8 13/20 0.89
CMKLR2 P46091 1/20 0.72
CMKLR1 Q99788 1/20 0.72
GPR34 Q9UPC5 3/20 0.65
PTPN1 P18031 2/20 0.64
PPARG P37231 1/20 0.61
CYP4F2 P78329 1/20 0.59
CYP4A11 Q02928 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122680 1.00 GPR132 (0.89) GPR132CMKLR2CMKLR1GPR34PTPN1
SCHEMBL1123644 0.98 GPR132 (0.93) GPR132CMKLR2CMKLR1GPR34PTPN1
SCHEMBL27638045 0.98 GPR132 (0.93) GPR132CMKLR2CMKLR1GPR34PTPN1
SCHEMBL1122810 0.98 GPR132 (0.93) GPR132CMKLR2CMKLR1GPR34PTPN1
SCHEMBL1123646 0.98 GPR132 (0.93) GPR132CMKLR2CMKLR1GPR34PTPN1
SCHEMBL1123379 0.97 GPR132 (0.95) GPR132CMKLR2CMKLR1PTPN1CYP4F2
SCHEMBL1122807 0.96 GPR132 (0.82) GPR132CMKLR2CMKLR1GPR34PTPN1
SCHEMBL1123316 0.94 GPR132 (0.87) GPR132CMKLR2CMKLR1GPR34PTPN1
SCHEMBL1123605 0.94 GPR132 (0.87) GPR132CMKLR2CMKLR1GPR34PTPN1
SCHEMBL27658925 0.94 GPR132 (0.79) GPR132CMKLR2CMKLR1GPR34PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1835914-A New benzamides as PPAR[upsilon] modulators S A L V A T LAB SA (ES) 2006-09-20 CN disclosed