Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 14/20 | 0.80 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.66 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.66 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.60 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123130 | 1.00 | GPR132 (0.80) | GPR132CMKLR2CMKLR1ITGB3ITGA2B | |
| SCHEMBL1123644 | 0.93 | GPR132 (0.93) | GPR132CMKLR2CMKLR1GPR34PTPN1 | |
| SCHEMBL1122810 | 0.93 | GPR132 (0.93) | GPR132CMKLR2CMKLR1GPR34PTPN1 | |
| SCHEMBL1123646 | 0.93 | GPR132 (0.93) | GPR132CMKLR2CMKLR1GPR34PTPN1 | |
| SCHEMBL27638045 | 0.93 | GPR132 (0.93) | GPR132CMKLR2CMKLR1GPR34PTPN1 | |
| SCHEMBL1123407 | 0.92 | GPR132 (0.77) | GPR132CMKLR2CMKLR1GPR34PTPN1 | |
| SCHEMBL27638098 | 0.92 | GPR132 (0.77) | GPR132CMKLR2CMKLR1GPR34PTPN1 | |
| SCHEMBL27638091 | 0.91 | GPR132 (0.66) | GPR132CMKLR2CMKLR1PTPN1PPARG | |
| SCHEMBL1122745 | 0.91 | GPR132 (0.66) | GPR132CMKLR2CMKLR1PTPN1PPARG | |
| SCHEMBL1122857 | 0.91 | GPR132 (0.67) | GPR132ITGB3ITGA2BGPR34PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |