Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 9/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.53 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.52 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.52 |
| ▸ | YAP1 | P46937 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122958 | 1.00 | GPR132 (0.62) | GPR132PPARGGAARAB9AERAP2 | |
| SCHEMBL1122960 | 1.00 | GPR132 (0.62) | GPR132PPARGGAARAB9AERAP2 | |
| SCHEMBL27659016 | 0.92 | GPR132 (0.74) | GPR132PPARGPTPN1CMKLR2CMKLR1 | |
| SCHEMBL1122856 | 0.92 | GPR132 (0.74) | GPR132PPARGPTPN1CMKLR2CMKLR1 | |
| SCHEMBL1122855 | 0.92 | GPR132 (0.74) | GPR132PPARGPTPN1CMKLR2CMKLR1 | |
| SCHEMBL27658963 | 0.92 | GAA (0.64) | GPR132PPARGGAARAB9AERAP2 | |
| SCHEMBL1122718 | 0.92 | GAA (0.64) | GPR132PPARGGAARAB9AERAP2 | |
| SCHEMBL1122715 | 0.92 | GAA (0.64) | GPR132PPARGGAARAB9AERAP2 | |
| SCHEMBL1122743 | 0.90 | GPR132 (0.76) | GPR132PPARGGAARAB9AERAP2 | |
| SCHEMBL1122705 | 0.90 | GPR132 (0.76) | GPR132PPARGGAARAB9AERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |