Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.57 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.43 |
| ▸ | FEN1 | P39748 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27659347 | 0.87 | ESR1 (0.63) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27659450 | 0.85 | ESR1 (0.77) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27659335 | 0.83 | ESR1 (0.70) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638496 | 0.82 | ESR1 (0.73) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638495 | 0.81 | ESR1 (0.67) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638488 | 0.81 | ESR1 (0.67) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638498 | 0.81 | ESR2 (0.71) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638485 | 0.81 | ESR2 (0.71) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638541 | 0.80 | ESR2 (0.62) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638499 | 0.79 | ESR1 (0.73) | ESR1ESR2ALOX5APFEN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | claimed |