Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.63 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27659450 | 0.90 | ESR1 (0.77) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27659335 | 0.88 | ESR1 (0.70) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL3923804 | 0.86 | ESR1 (0.76) | ESR1ESR2 | |
| SCHEMBL27638488 | 0.85 | ESR1 (0.67) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638495 | 0.85 | ESR1 (0.67) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27659409 | 0.83 | ESR1 (0.45) | ESR1ESR2ALOX5APFEN1PGR | |
| SCHEMBL27659347 | 0.83 | ESR1 (0.63) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638541 | 0.82 | ESR2 (0.62) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638498 | 0.81 | ESR2 (0.71) | ESR1ESR2ALOX5APFEN1QPCT | |
| SCHEMBL27638485 | 0.81 | ESR2 (0.71) | ESR1ESR2ALOX5APFEN1QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | claimed |
| CN-1823046-A | Phenyl quinolines and their use as estrogen receptor modulators | WYETH CORP (US) | 2006-08-23 | — | — | CN | disclosed |