Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638611 | 0.93 | HCAR2 (0.53) | TSHRHCAR2ATMTDP1CYP3A4 | |
| SCHEMBL23494025 | 0.87 | TSHR (0.63) | TSHRATMTDP1CYP3A4ALDH1A1 | |
| SCHEMBL11745052 | 0.85 | TSHR (0.53) | TSHRHCAR2ATMTDP1CYP3A4 | |
| SCHEMBL1453623 | 0.85 | TSHR (0.53) | TSHRHCAR2ATMTDP1CYP3A4 | |
| SCHEMBL28014440 | 0.80 | TSHR (0.53) | TSHRATMTDP1CYP3A4ALDH1A1 | |
| SCHEMBL11437882 | 0.79 | TSHR (0.49) | TSHRHCAR2ATMTDP1CYP3A4 | |
| SCHEMBL11748242 | 0.79 | TSHR (0.47) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL11437885 | 0.79 | TSHR (0.49) | TSHRHCAR2ATMTDP1CYP3A4 | |
| SCHEMBL15355365 | 0.79 | TSHR (0.47) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL11749700 | 0.79 | TSHR (0.47) | TSHRHCAR2ATMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100415778-C | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE S P A (IT) | 2008-09-03 | — | — | CN | disclosed |
| CN-1714105-A | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE S P A (IT) | 2005-12-28 | — | — | CN | disclosed |